The presentation will first focus on the development of this class of catalytic polymerization.
　　The evolving mechanistic understanding will be discussed based on our synthetic explorations and kinetic studies. The scope and limitation of the polymerization will be then discussed, including the suitable monomer types for the polymerization and the control of the microstructure and architecture of the polymer products. 
　　The properties of the poly(-alanoid)s (X = NR) and poly(-alanine) (X = NH) synthesized via COP of aziridines will be then presented. The superb protein-adsorption resistance of the highly water-soluble members of poly(-alanoid)s (R = Me or Et) is demonstrated by surface plasma resonance spectroscopy (Figure 1).  Poly(-alanoid-block--alanine)s are explored as the building blocks for supramolecular assemblies on the basis of the propensity of the -alanine block to form flat, extended sheet-like structure.